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KMID : 0356920150680060586
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Korean Journal of Anesthesiology
2015 Volume.68 No. 6 p.586 ~ p.593
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Clinical and psychological characteristics of propofol abusers in Korea: a survey of propofol abuse in 38, non-healthcare professionals
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:Kim Eun-Jung
:Kim Seon-Hwa/:Hyun Yang-Jin/:Noh Yeon-Keun/:Jung Ho-Sang/:Han Soon-Young/:Park Chan-hye/:Choi Byung-Moon/:Noh Gyu-Jeong
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Abstract
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Background : The aim of this study is to investigate the characteristics of propofol abuse based on the results of a survey analysis of abusers among non-healthcare professionals in Korea.
Methods : Thirty-eight propofol abusers were questioned between October and December 2010, and were enrolled and voluntarily participated in a structured survey consisting of an interview and completing a previously prepared questionnaire. The questionnaire was divided into three distinct parts: part 1 dealt with the history of propofol abuse; part 2 highlighted the problems caused by propofol abuse; and part 3 enquired regarding demographics of abusers.
Results : Thirty-one (81.6%) of the 38 interviewees abused propofol for more than one year. During the last 12 months, 34 (89.0%) received propofol at two or three times a week. The minimum and maximum amounts of propofol (median, range) administered each time were 500 (100, 1000) and 2000 (500, 4000) mg, respectively. Stress relief and the maintenance of a sense of well-being were quoted the most important reasons for the first-time administration of propofol and its subsequent abuse, respectively. The majority of abusers (36.0, 97.3%) reported a sense of pleasure or euphoria at the time of their propofol injection. Withdrawal symptoms occurred in five abusers (13.2%). Thirteen (36.1%) reported disruptions in their work life. None of the respondents had previously admitted to and or reported abuse of any other controlled substances.
Conclusions : These results provided reference data for the regulation of propofol in Korea as a controlled substance and may also be of interest to international agencies in other countries.
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KEYWORD
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Abuse, General population, Propofol
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